Loss of chromosome 10, retinoblastoma and deleted-in-colon-carcinoma (DCC) proteins in glioblastomas
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چکیده
but were increased around areas of necrosis and around blood vessels. No relationship between tumour cell proliferation and necrosis was detected. Conclusions: Tumour cell proliferation is concentrated around blood vessels in glioblastomas. Blood vessel proliferation, but not tumour cell proliferation, is related to areas of necrosis and the presence of macrophages in glioblastomas. Targeting of blood vessel proliferation and macrophages within glioblastoma may present a therapeutic strategy for treatment of these devastating tumours.
منابع مشابه
A combined analysis of the Deleted in Colon Cancer (DCC) and the p53 proteins expression in gastric cancer
Title: A combined analysis of the Deleted in Colon Cancer (DCC) and the p53 proteins expression in gastric cancer. Summary Background: Loss of acitivity of tumor suppressor genes is considered a fundamental step in a genetic model of
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